Circulating cell-free DNA in cancer

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Abstract

This papers deals with the preanalytical and analytical phase of cell-free DNA analysis, highlighting some criticism on sample collection and extraction. We describe a method to accurately quantify total cfDNA in plasma and our particular approach to the measurement of tumor deriving cfDNA.

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Pinzani, P., Salvianti, F., Orlando, C., & Pazzagli, M. (2014). Circulating cell-free DNA in cancer. Methods in Molecular Biology, 1160, 133–145. https://doi.org/10.1007/978-1-4939-0733-5_13

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