Abstract
We present Cancer Clonal Evolution Simulator (CCES)—a simulation system of the clonal growth of cancer cell populations with arbitrary selection patterns. It is possible record the life history of each separate cancer cell and to track propagation of mutations over cancer cells phylogenies at the scale of hundreds of thousands of cancer cells. Thanks to efficient implementation our system enables studying evolution of tumor tissues at the scale of hundreds of thousands of cancer cells.
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Szymiczek, K., Gruca, A., & Polanski, A. (2018). CCES: Cancer clonal evolution simulation program. In Advances in Intelligent Systems and Computing (Vol. 659, pp. 172–181). Springer Verlag. https://doi.org/10.1007/978-3-319-67792-7_18
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