Incorporation of Tritiated Water (HTO) or Organically Bound Tritium (OBT) into Amino Acids of Rat Brain Proteins

Abstract

Tritium incorporation/Rats/Amino acids. Three generations of rats were long-term exposed to HTO in drinking water at activity of 37.0 kBq/g ml or to food containing OBT at activity of 48.1 kBq/g. The rats consumed tritiated water and tritiated food ad libitum. The parent females P0 were exposed for 64 days, the F1 and F2 generation were lifetime exposed and F3 generation during whole intrauterine life. It was found that the amount of tritium incorporated into rat brain proteina mino acid safter administration of tritiated food was higher than after administration of tritiated water and was the highest in rats exposed during their intrauterine life. © 1985, Journal of Radiation Research Editorial Committee. All rights reserved.