Chemical analysis of an Indonesian sponge sample has provided three new 3-alkylpiperidine alkaloids, tetradehydrohaliclonacyclamine A, its mono-N-oxide derivative, and a 2-epi isomer. The absolute structure of tetradehydrohaliclonacyclamine A has been established by X-ray crystallography from anomalous dispersion effects using Cu radiation, which determined that the absolute configuration is 2S, 3S, 7S, 9S while an HPLC study revealed that the alkaloid is enantiomerically pure. © 2010 Elsevier Ltd. All rights reserved.
CITATION STYLE
Mudianta, I. W., Katavic, P. L., Lambert, L. K., Hayes, P. Y., Banwell, M. G., Munro, M. H. G., … Garson, M. J. (2010). Structure and absolute configuration of 3-alkylpiperidine alkaloids from an Indonesian sponge of the genus Halichondria. Tetrahedron, 66(14), 2752–2760. https://doi.org/10.1016/j.tet.2010.01.068
Mendeley helps you to discover research relevant for your work.