Synthesis of Bio-composite CHA/PVA/Alginate as Bone Substitute Material

Abstract

The main inorganic constituent of human bone is carbonated-hydroxyapatite (CHA). The CHA powder had been successfully synthesized by using chicken eggshell through microwave assisted precipitation methods. In the application, the biomaterials needed by orthopaedic doctors were in the form of scaffold. The addition of PVA and alginate to CHA can improve mechanical properties and affect the pores. The freeze-drying method was used to synthesize bio-composite scaffold. The FTIR result showed that spectrums correspond to functional group of PO43-, OH-, CO32- which were the characteristic of CHA. The elastic scaffold was produced in this research. The scaffold mechanical test results showed that the higher PVA content showed the higher mechanical properties. The phase composition was evaluated by XRD and indicated the presence of CHA. The morphology of the sample was evaluated by SEM which formed pores. These scaffolds showed good prospects for bone substitute material.