This chapter describes the types of irreversible inhibition of drug-metabolizing enzymes and the methods commonly employed to quantify the irreversible inhibition and subsequently predict the extent and time course of clinically important drug-drug interactions. © Springer Science+Business Media, LLC 2014.
CITATION STYLE
Mohutsky, M., & Hall, S. D. (2014). Irreversible enzyme inhibition kinetics and drug-drug interactions. Methods in Molecular Biology, 1113, 57–91. https://doi.org/10.1007/978-1-62703-758-7_5
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