Abstract
An accumulating body of evidence shows significant similarities between cellular processes involved in neurodegeneration and those involved in neurodevelopment. Most striking, in Alzheimer's disease, cell cycle re‐entry appears to be a pathological signature of the disease that also occur in brain development. Such inappropriate reactivation of a fetal program is likely to play a key role in both the etiology and pathogenesis of disease.
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CITATION STYLE
Zhu, X., Casadesus, G., Webber, K. M., Atwood, C. S., Bowen, R. L., Perry, G., & Smith, M. A. (2008). Parallels Between Neurodevelopment and Neurodegeneration: A Case Study of Alzheimer’s Disease. In Handbook of Neurochemistry and Molecular Neurobiology (pp. 147–155). Springer US. https://doi.org/10.1007/978-0-387-32671-9_7
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