e-PWV: A Web Application for Assessing Online Carotid-Femoral Pulse Wave Velocity

Abstract

This article presents e-PWV, a web application for the determination of Pulse Wave Velocity (PWV) running on a web platform called NooLib. e-PWV has been applied on signals recorded by an ultrasound system (PWVet, Aloka, Japan) and representing the arterial diameter changes in carotid and femoral sites. PWVet measurements were compared to PWV recorded by a tonometric technique (PWVpp, PulsePen, Italy). The study was conducted on 120 patients. We found an excellent correlation of r = 0.95 between PWVet et PWVpp (P< 0.0001; 95% confidence interval of 0.91–0.96; PWVet= 0.88 × PWVpp+ 0.57). We observed a small offset of - 0.33 ms- 1 on the Bland-Altman plot with a limit of agreement from - 2.21 to 1.54 ms- 1. Our results suggest that e-PWV application can produce online a reliable marker of the regional aortic stiffness using an echotracking system.