Use of rabies vaccines after reconstitution and storage

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Abstract

Storing freshly reconstituted purified chick embryo rabies vaccine at 4°C for 1 week allowed use of <1 ampoule of 1.0 mL for 1 patient for day 0, 3, and 7 immunizations, representing considerable savings in vaccine and also possibly allowing use of this cost-saving regimen in centers that see <1 rabies-exposed patient daily. The 90-day booster dose mandated in the current intradermal regimen may not be necessary if the day 28 dose is doubled, eliminating 1 clinic visit at no additional cost in vaccine.

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Khawplod, P., Tantawichien, T., Wilde, H., Limusanno, S., Tantawichien, T., Saikasem, A., & Raksakate, S. (2002). Use of rabies vaccines after reconstitution and storage. Clinical Infectious Diseases, 34(3), 404–406. https://doi.org/10.1086/324507

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