Abstract
Colorectal cancer (CRC) is a prominent source of cancer-related deaths across the world. AP-1 is involved in CRC growth and metastasis. AP-1 is a transcription factor that regulates many oncogenic transduction pathways. In the current chapter, we discuss the importance of AP-1 on CRC growth and metastasis. Additionally, we discuss the mechanism of genistein, a tyrosine kinase inhibitor, and its effect on CRC treatment.
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Merchant, N., Prasad, G. L. V., & Nagaraju, G. P. (2018). Genistein and its role in regulation of AP-1 in colorectal cancer. In Role of Transcription Factors in Gastrointestinal Malignancies (pp. 99–104). Springer Singapore. https://doi.org/10.1007/978-981-10-6728-0_8
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