Aspergillus laryngotracheobronchitis presenting as stridor in a patient with peripheral T cell lymphoma

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Abstract

Invasive aspergillosis is a serious opportunistic infection in immunocompromised patients. The case history is described of a 44 year old patient with peripheral T cell lymphoma who developed hoarseness and stridor after chemotherapy. Aspergillus fumigatus was isolated repeatedly from the sputum. Bronchoscopic examination showed symmetrical creamy-white exophytic lesions involving both vocal cords and the supraglottic area. There was diffuse tracheobronchitis with multiple raised cream-coloured plaques in the trachea which histologically consisted of numerous septate branching hyphae consistent with Aspergillus species. The lesions responded to systemic treatment with amphotericin B.

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Kuo, P. H., Lee, L. N., Yang, P. C., Chen, Y. C., & Luh, K. T. (1996). Aspergillus laryngotracheobronchitis presenting as stridor in a patient with peripheral T cell lymphoma. Thorax, 51(8), 869–870. https://doi.org/10.1136/thx.51.8.869

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