Abstract
We report here an efficient and green method for Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea catalyzed by Brønsted acidic ionic liquid [Btto][p-TSA] under solvent-free conditions. Compared to the classical Biginelli reaction conditions, the present method has the advantages of giving good yields, short reaction times, near room temperature conditions and the avoidance of the use of organic solvents and metal catalyst.
Author supplied keywords
Cite
CITATION STYLE
Zhang, Y., Wang, B., Zhang, X., Huang, J., & Liu, C. (2015). An efficient synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones and thiones catalyzed by a novel brønsted acidic ionic liquid under solvent-free conditions. Molecules, 20(3), 3811–3820. https://doi.org/10.3390/molecules20033811
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
