The general question of what constitutes bio-curation for rule-based modelling of cellular signalling is posed. A general approach to the problem is presented, based on rewriting in hierarchies of graphs, together with a specific instantiation of the methodology that addresses our particular bio-curation problem. The current state of the ongoing development of the KAMI (Knowledge Aggregator & Model Instantiator) bio-curation tool, based on this approach, is detailed along with our plans for future development.
CITATION STYLE
Harmer, R., Cornec, Y. S. L., Légaré, S., & Oshurko, I. (2017). Bio-curation for cellular signalling: The KAMI project. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 10545 LNBI, pp. 3–19). Springer Verlag. https://doi.org/10.1007/978-3-319-67471-1_1
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