Addenbrooke’s Cognitive Examination (ACE) and Its Revision (ACE-R)

Abstract

The Addenbrooke's Cognitive Examination (ACE) and its revised version (ACE-R) are theoretically motivated revisions of the Mini-Mental State Examination (MMSE) which attempt to address the neuropsychological omissions and improve the screening performance of the latter. Though taking longer to administer than the MMSE, and therefore best suited to specialist settings, both ACE and ACE-R have proved to be acceptable to patients and have shown excellent performance in identifying cognitive impairment in a variety of clinical situations (Alzheimer's disease, frontotemporal lobar degenerations, parkinsonian syndromes, stroke and vascular dementia, brain injury). Subscores of the ACE/ACE-R may be useful for the differentiation of Alzheimer's disease from frontotemporal lobar degeneration (the VLOM ratio) and of Alzheimer's disease from semantic dementia (the SI index). ACE/ACE-R utility has prompted translation into various languages. (PsycINFO Database Record (c) 2019 APA, all rights reserved) (Source: chapter)