Numerous eruptive lesions of panniculitis associated with group A streptococcus bacteremia in an immunocompetent child

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Abstract

A previously healthy 13-month-old boy developed group A β-hemolytic streptococcus bacteremia coinciding with numerous eruptive subcutaneous lesions primarily on his extremities. Skin biopsy revealed infectious panniculitis; gram-positive cocci were present within both fat lobules and septa. Molecular genetic analysis of an isolate from the patient's blood revealed an emm type 4 organism displaying the emm chromosomal pattern E that is characteristic of opacity factor-producing strains; the organism also harbored the gene encoding for streptococcal pyrogenic exotoxin C (speC). To our knowledge, this clinical presentation has not yet been described in the spectrum of infections directly caused by group A β-hemolytic streptococci.

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Pao, W., Duncan, K. O., Bolognia, J. L., Carroll, C. B., Hotez, P. J., & Bessen, D. E. (1998). Numerous eruptive lesions of panniculitis associated with group A streptococcus bacteremia in an immunocompetent child. Clinical Infectious Diseases, 27(3), 430–433. https://doi.org/10.1086/514685

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