Transdermal drug delivery offers a number of advantages including sustained release, improved patient compliance, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect. However, only few medications can be delivered through the transdermal route in therapeutic amounts. NSAIDs are consisted of a group of drugs that are widely used, but their use by oral or transdermal system is limited due to a number of side effects. Therefore, NSAIDs are ideal candidates for delivery via microneedles, a relatively new method of drug delivery. A new concept was introduced known as microneedles and these could be used to effectively deliver drugs using micron-sized needles in a minimally invasive and painless manner. Microneedles can be used to enhance transdermal drug delivery and they can be fabricated in different forms.
CITATION STYLE
Vranić, E., Tucak, A., Vrabac, D., Rahić, O., Elezović, A., & Hadžiabdić, J. (2017). Microneedle-assisted delivery of nsaids. In IFMBE Proceedings (Vol. 62, pp. 311–316). Springer Verlag. https://doi.org/10.1007/978-981-10-4166-2_47
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