Biostimulation and biorevitalization: effects on human skin fibroblasts

Abstract

Aesthetic medicine uses many injective techniques; biostimulation (BS) and biorevitalization (BR) are among these. The term BS indicates stimulation of the anabolic functions of dermal fibroblasts such as replication, protein synthesis and production of extracellular matrix components (ECM). BR instead uses the same injective technique but different medical devices. It is a direct supplementation of hyaluronic acid (HA) alone or added to other molecules (i.e. vitamins). This study discusses BS and BR and their effects on human skin fibroblasts.