Elastic registration algorithm of medical images based on fuzzy set

Abstract

An elastic registration algorithm based on fuzzy set is proposed in the paper, The fuzziness of medical images is shown in two aspects: (1) the intensity of the pixels in medical images is fuzzy. The same kind of tissue may has different intensity and the same intensity may correspond to different tissues in one image; (2) the space position of image pixel is fuzzy. In the paper, we applied the fuzzy theory to the first aspect and presented the concept of fuzzy mutual information and its optimization method. For the second aspect, a multiresolution registration method based on fuzzy set and its optimization method is presented. 16 groups of experiments have been done and the results showed that the elastic registration algorithm based on fuzzy set can improve the accuracy and robustness of registration algorithm greatly. © Springer-Verlag Berlin Heidelberg 2006.