In silico prediction of allergenic proteins

Abstract

Currently, the prediction of new allergens is becoming important due to use of genetically modified (GM) foods and biopharmaceuticals. In this chapter, we describe how to use four popular allergenic prediction servers: (1) Structural Database of Allergenic Proteins (SDAP), (2) Allermatch, (3) Evaller 2, and (4) AlgPred. The first two prediction servers are based on traditional approaches, whereas Evaller 2 and AlgPred use sophisticated machine learning techniques. © Springer Science+Business Media New York 2014.