Physical characterisation of a polycaprolactone tissue scaffold

Abstract

The suitability of tissue scaffolds to act as temporary housings for culturing cells depends on their size, shape and structural characteristics. Factors such as porosity, the type of pores present and their size distribution play a key role in ensuring appropriate levels of metabolite transport as well as influencing scaffold degradation behavior and any associated changes in mechanical resilience. This paper presents the findings of a preliminary study of the structure of a range of porous polycaprolactone tissue scaffolds manufactured using the particulate leaching technique.