Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium

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Abstract

Achillinin A (2β,3β-epoxy-1α,4β,10α- trihydroxyguai- 11(13)-en-12,6α-olide, 1), a new guaianolide isolated from the flower of Achillea millefolium, exhibited potential antiproliferative activity to A549, RERF-LCkj and QG-90 cells with 50% inhibitory concentration (IC 50) values of 5.8, 10 and 0.31μM, respectively.

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Li, Y., Zhang, M. L., Cong, B., Wang, S. M., Dong, M., Sauriol, F., … Kiyota, H. (2011). Achillinin A, a cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. Bioscience, Biotechnology and Biochemistry, 75(8), 1554–1556. https://doi.org/10.1271/bbb.110234

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