Acanthamoeba keratitis in Sudan: outcome of ketoconazole treatment in six patients

Abstract

In an exploration of the acanthamoebic aetiology of chronic keratitis cases [not responding to antibiotics, antiviral or antifungal therapy], 138 Sudanese patients were seen over a 2-year period at two teaching eye hospitals in Khartoum State. Six [4.3%] of these patients were found to be suffering from Acanthamoeba keratitis. The present study focuses on the good outcome of oral ketoconazole in four patients at 18 months follow up period. The drug oral route, convenient frequency of doses, minimal side effects and availability at reasonable price favour ketoconazole therapy