Abstract
No current non-invasive method is capable of assessing the efficacy of brain tumor therapy early during treatment. We outline an approach that evaluates tumor activity via statistical analysis of vessel shape using vessels segmented from MRA. This report is the first to describe the changes in vessel shape that occur during treatment of metastatic brain tumors as assessed by sequential MRA. In this preliminary study of 16 patients undergoing treatment for metastatic breast cancer we conclude that vessel shape may predict tumor response several months in advance of traditional methods. © Springer-Verlag Berlin Heidelberg 2006.
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CITATION STYLE
Bullitt, E., Lin, N. U., Ewend, M. G., Zeng, D., Winer, E. P., Carey, L. A., & Smith, J. K. (2006). Tumor therapeutic response and vessel tortuosity: Preliminary report in metastatic breast cancer. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 4191 LNCS-II, pp. 561–568). Springer Verlag. https://doi.org/10.1007/11866763_69
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