Biological characteristics of rubella virus as assayed in a human amnion culture system

Abstract

We have briefly reviewed observations stemming from the finding that rubella virus may be grown in cultures of human amnion cells with the production of specific cytopathic changes. Rubella research is now in a phase of rapid development. While it is hoped that the information accumulated to date will not in the future be proven erroneous, it can be confidently predicted that the somewhat laborious and poorly standardized methodology now available for the investigation of rubella virus will undergo rapid refinement and simplification. Rubella will then move from the province of the research bench to the routine diagnostic laboratory. © 1965 Springer-Verlag.