Instructing macrophages to fight cancer

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Abstract

Two drug-loaded nanoparticle formulations that preferentially accumulate within tumour-associated macrophages induce macrophage repolarization to a tumoricidal state that leads to potent antitumour activity in multiple murine models of cancer.

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Gustafson, H. H., & Pun, S. H. (2018). Instructing macrophages to fight cancer. Nature Biomedical Engineering, 2(8), 559–561. https://doi.org/10.1038/s41551-018-0276-0

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