High prevalence of blaNDM-1 carbapenemase-encoding gene and 16S rRNA armA methyltransferase gene among Acinetobacter baumannii clinical isolates in Egypt

Abstract

The main objective of this study was to decipher the molecular mechanism of resistance to carbapenems and aminoglycosides in a large series of 150 Acinetobacter baumannii clinical isolates collected from July 2012 to September 2013 in Egypt. We report for the first time the emergence of blaNDM-1 and the cooccurrence of 16S rRNA methylase armA with blaNDM-1 and blaOXA-23 in Egyptian hospitals. Multilocus sequence typing identified 27 distinct sequence types, 11 of which were novel.