In vitro antioxidant and anthelmintic properties of rhizome extracts of Hedychium spicatum

Abstract

In the present study, different extracts of Hedychium spicatum were evaluated for in vitro antioxidant property by ABTS, DPPH and nitric oxide free radical scavenging assay. The methanolic extracts showed IC50 minimum as compared to other extracts. Total flavonoid and phenolic contents were determined and methanolic extracts showed the maximum contents of flavonoids (38.70±36.63 mg of rutin equivalent/g of extract) and phenolic (60.01±1.46 mg of gallic acid equivalent/g of extracts), respectively. The in vitro anthelmintic efficacy of methanolic extract @ 2%, 4%, 6% and 8% concentrations against the Hemonchus contortus was found maximum as compared to other extracts and standard drug thiabendazole. The time of paralysis and time of death of the parasite were recorded and was found minimum for methanolic extract against Hemonchus contortus than the other extracts. Thus, the extracts of the Hedychium spicatum may be used for therapeutic purposes in animal and human health.