Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA)

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Abstract

Background: Susac syndrome is a rare condition involving the brain, retina, and cochlea. Electroencephalogram (EEG) findings from published case reports show mainly generalized slowing. Case report: A 30-year-old man presented with acute onset of superior vision loss, unsteady gait, and hearing loss. This was accompanied by short-term memory loss and behavioral and mood changes. MRI showed multiple white matter hyperintensities. The EEG showed frontal intermittent rhythmic delta activity. A diagnosis of Susac syndrome was made and treatment with methylprednisolone, ASA, and Nimodipine was instituted. At one-year follow-up, bilateral hearing loss, mild visual impairment, and mood changes were still apparent. Conclusions: Frontal intermittent rhythmic delta activity can be seen in Susac syndrome.

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Woolridge, D., Stefanelli, M., & Hoppe, B. (2006). Susac syndrome with frontal intermittent rhythmic delta activity (FIRDA). Canadian Journal of Neurological Sciences, 33(4), 403–406. https://doi.org/10.1017/S0317167100005369

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