Mortar-Pestle and Microwave Assisted Regioselective Nitration of Aromatic Compounds in Presence of Certain Group V and VI Metal Salts under Solvent Free Conditions

Abstract

Solvent – free Mortar-pestle (grinding) and microwave-assisted nitration reactions (MWANR’s) underwent smoothly in the presence of group V and VI metal salts with high regio-selectivity for anilides, moderately- and non-activated aro-matic compounds. The reactions were conducted under solvent-free conditions, which afforded good to excellent yields. The observed reaction times in MW assisted conditions are in the range of only few minutes.