A novel mannose-specific lectin, named CGL1 (15.5 kDa), was isolated from the oyster Crassostrea gigas. Characterization of CGL1 revealed that it has strict specificity for the mannose monomer and for high mannose-type N-glycans (HMTGs). The primary and crystal structure of CGL1 did not show any homology with known lectins. These characteristics of CGL1 may be helpful as a research tool and for clinical applications. We show a purification protocol of CGL1 from the Pacific oyster.
CITATION STYLE
Unno, H., & Hatakeyama, T. (2020). Mannose-Specific oyster lectin CGL1. In Methods in Molecular Biology (Vol. 2132, pp. 621–628). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0430-4_53
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