Semi-synchronous activation in scale-free boolean networks

Abstract

We study the dynamics of Boolean networks of the scale-free type. The model takes into account the topology and abstracts recent findings about real genetic regulatory networks. We propose a new, more biologically plausible, semi-synchronous update scheme on networks of larger sizes. We simulate statistical ensembles of networks and discuss the attractors of the dynamics, showing that it is compatible with theoretical biological network models. Moreover, then model demonstrates interesting scaling abilities as the size of the networks is increased. © Springer-Verlag Berlin Heidelberg 2007.