Protein folding pathways implementing dihedral angle variable speed

Abstract

Protein folding remains as an impossible riddle biologist must solve. Its huge computational requirements make it difficult to obtain clues regarding protein folding nature. The procedure presented in this paper presents a fast algorithm capable of obtaining hundreds of intermediate positions between the unfolded and the folded structures of several proteins. Presented algorithms make use of the balls and rods approach for protein structure modelization. In this paper, structures are normalized in order to minimize differences between experimental data and the kinematic model used in this paper.