Histamine and biogenic amines

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Abstract

Histamine is a simple chemical substance with a molecular weight of 111 Da. It was discovered in the ergot in 1911. Many great discoveries in medicine are based on coincidences, errors, or sheer carelessness. This is true of histamine as well. Several years later it was discovered that the ergot investigated at the time was contaminated with histamine-producing bacteria and the ergot itself does not contain histamine.

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Jarisch, R., Wantke, F., Raithel, M., & Hemmer, W. (2015). Histamine and biogenic amines. In Histamine Intolerance: Histamine and Seasickness (pp. 3–43). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-55447-6_2

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