Cross-dehydrogenative coupling reactions of sp3-hybridized C-H bonds.

Abstract

New methodologies in cross-coupling reaction using C-H bonds as substrates is of great interest due to the challenges associated with C-H bond activation and the potential to streamline synthesis by the elimination of preactivation of coupling reagents. In this chapter, recent developments in oxidative cross-coupling reactions will be presented with the focus on the functionalization of sp3 C-H bonds with other C-H bonds.