Glycoproteins play an important role in cell signaling and cell-cell interaction. The alterations of glycoproteins are often relevant to progression of diseases, and these changed glycoproteins can be important biomarkers. The lectin-based glycoproteomic technology has extensively been used for high-throughput screening of potential glycoprotein biomarkers. Here we describe a multi-lectin af fi nity chromatography and label-free quantitative glycoproteomic approach for discovery of glycoprotein biomarkers relevant to differentiation of glioblastoma stem cells.
CITATION STYLE
He, J., Liu, Y., Wu, J., & Lubman, D. M. (2013). Analysis of glycoproteins for biomarker discovery. Methods in Molecular Biology. https://doi.org/10.1007/978-1-62703-360-2_10
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