Efecto del ejercicio sobre las subpoblaciones HDL, la enzima lecitina-colesterol acil-transferasa y la proteína transportadora de ésters de colesterol en estudiantes de Medicina

Abstract

Objective: To evaluate exercise effect on HDL subpopulations, lecithin-cholesterol acyltrans-ferase enzyme and ester transfer protein cholesterol levels in medical students.Method: Population was divided voluntarily into 2 groups, exercise and no exercise. Waistcircumference and body mass index were measured; subfractions HDL2and HDL3by ion preci-pitation and LCAT and CETP enzymes Enzyme-Linked Immuno-Sorbent Assay (ELISA).Results: Lipidrisk profile increased in both groups; HDL, HDL2and HDL3decreased in bothgroups, but only the HDL2decreased significantly in students who exercised. LCAT and CETPremained without significant changes, however, in the exercise group, there was statisticallysignificant decrease in HDL2and LCAT in women.Conclusions: This study shows that exercise does alter some variables such as waist circum-ference, body mass index and HDL3. These changes are dependent on gender, but despite theintervention of 3 months with an exercise program, it fails reducing lipid risk factors in this medi-cal student populations, given their environment, which complicates their metabolic responseto exercise.