Studies on the Susceptibility to Convulsions in Animals Receiving Abuse Doses of Aspartame

  • Garattini S
  • Caccia S
  • Romano M
  • et al.
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Abstract

Aspartame and its major metabolite phenylalanine were studied for their capacity to potentiate metrazol, electroshock, and quinolinic-acid-induced seizures in rats. Pretreatment with 0.75 and 1 g/kg aspartame or 0.250 and 0.500 g/kg phenylalanine administered by...

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Garattini, S., Caccia, S., Romano, M., Diomede, L., Guiso, G., Vezzani, A., & Salmona, M. (1988). Studies on the Susceptibility to Convulsions in Animals Receiving Abuse Doses of Aspartame. In Dietary Phenylalanine and Brain Function (pp. 131–143). Birkhäuser Boston. https://doi.org/10.1007/978-1-4615-9821-3_15

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