Note of clarification of data in the paper entitled association between BRIP1 (BACH1) polymorphisms and breast cancer risk

Abstract

With great interest, we read the recent article entitled “Association between BRIP1 (BACH1) polymorphisms and breast cancer risk: a meta-analysis” published online in Pabalan et al. (Breast Cancer Res Treat 137:553–558, 2013). This article suggests that overall summary estimates imply no associations but suggest susceptibility among carriers of the C47G polymorphism and Pro-Ser genotype in premenopausal women. The result is encouraging. Nevertheless, several key issues in this meta-analysis are worth noticing.