A new 3ô-prenyloxypsoralen from the raw fruits of aegle marmelos and its cytotoxic activity

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Abstract

One new furanocoumarin, 3ô-prenyloxypsoralen (1), and two known furanocoumarins, imperatorin (2) and xanthotoxin (3) were isolated from the raw fruits of Aegle marmelos. The structures of the isolated coumarins were confirmed by spectroscopic evidence. Compound 1 exhibited moderate cytotoxic activity against HEK293, HeLa, MCF7, and HT29 cell lines with IC50 values of 31.2, 44.8, 36.3, and >50.0 ôg/mL, respectively.

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Radchatawedchakoon, W., Bamrungsuk, S., Namwijit, S., Apiratikul, N., Sakee, U., & Yingyongnarongkul, B. E. (2015). A new 3ô-prenyloxypsoralen from the raw fruits of aegle marmelos and its cytotoxic activity. Natural Product Communications, 10(11), 1973–1975. https://doi.org/10.1177/1934578x1501001142

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