High-speed crystal detection and characterization using a fast-readout detector

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Abstract

A novel raster-scanning method combining continuous sample translation with the fast readout of a Pilatus P6M detector has been developed on microfocus beamline I24 at Diamond Light Source. This fast grid-scan tool allows the rapid evaluation of large sample volumes without the need to increase the beam size at the sample through changes in beamline hardware. A slow version is available for slow-readout detectors. Examples of grid-scan use in centring optically invisible samples and in detecting and characterizing numerous microcrystals on a mesh-like holder illustrate the most common applications of the grid scan now in routine use on I24. © 2010 International Union of Crystallography Printed in Singapore - All rights reserved.

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Aishima, J., Owen, R. L., Axford, D., Shepherd, E., Winter, G., Levik, K., … Evans, G. (2010). High-speed crystal detection and characterization using a fast-readout detector. Acta Crystallographica Section D: Biological Crystallography, 66(9), 1032–1035. https://doi.org/10.1107/S0907444910028192

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