Dynamic aerobic exercise induces baroreflex improvement in diabetic rats

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Abstract

The objective of the present study was to investigate the effects of an acute aerobic exercise on arterial pressure (AP), heart rate (HR), and baroreflex sensitivity (BRS) in STZ-induced diabetic rats. Male Wistar rats were divided into control (n = 8) and diabetic (n = 8) groups. AP, HR, and BRS, which were measured by tachycardic and bradycardic (BR) responses to AP changes, were evaluated at rest (R) and postexercise session (PE) on a treadmill. At rest, STZ diabetes induced AP and HR reductions, associated with BR impairment. Attenuation in resting diabetes-induced AP (R: 103 2 versus PE: 111 3 mmHg) and HR (R: 290 7 versus PE: 328 10 bpm) reductions and BR dysfunction (R: - 0.70 0.06 versus PE: - 1.21 0.09 bpm/mmHg) was observed in the postexercise period. In conclusion, the hemodynamic and arterial baro-mediated control of circulation improvement in the postexercise period reinforces the role of exercise in the management of cardiovascular risk in diabetes. © 2012 Luciana Jorge et al.

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APA

Jorge, L., Pureza, D. Y. D., Dias, D. D. S., Conti, F. F., Irigoyen, M. C., & De Angelis, K. (2012). Dynamic aerobic exercise induces baroreflex improvement in diabetic rats. Experimental Diabetes Research, 2012. https://doi.org/10.1155/2012/108680

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