Three tetracyclic triterpenoic acids from dysoxylum densiflorum and their antibacterial activities

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Abstract

This paper reports the chemical isolation and antibacterial properties of terpenoid components of Dysoxylum densiflorum. Three new tetracyclic triterpenoic acids, densiflorinic acids A-C (1-3), were isolated from the acetone extract of the plant's leaves. The structures of the three compounds were determined mainly by extensive analysis of 1-D and 2-D NMR spectroscopic data. On antibacterial evaluation, the highest activity was shown by compound 1 against Bacillus subtilis with an IC50 of 26.5 ×M.

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Dharmayani, N. K. T., Juliawaty, L. D., & Syah, Y. M. (2016). Three tetracyclic triterpenoic acids from dysoxylum densiflorum and their antibacterial activities. Natural Product Communications, 11(8), 1081–1083. https://doi.org/10.1177/1934578x1601100812

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