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Development of a Large Scale Process for the Production of Recombinant Truncated Factor VIII in CHO Cells under Cell Growth Arrest Conditions

  • Chotteau V
  • Björling T
  • Boork S
  • et al.
Springer Netherlands, (2001), 287-292
DOI: 10.1007/978-94-010-0369-8_67
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Abstract

A large scale biopharmaceutical process has been developed for the production of a genetically engineered variant of coagulation factor VIII. Factor VIII is the coagulation protein that is defective or missing in hemophilia A. Two challenging techniques, ceil growth...

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Chotteau, V., Björling, T., Boork, S., Brink-Nilsson, H., Chatzissavidou, N., Fenge, C., … Drapeau, D. (2001). Development of a Large Scale Process for the Production of Recombinant Truncated Factor VIII in CHO Cells under Cell Growth Arrest Conditions. In Animal Cell Technology: From Target to Market (pp. 287–292). Springer Netherlands. https://doi.org/10.1007/978-94-010-0369-8_67

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