Raynaud’s phenomenon presents clinically as cold mottled skin and most commonly involves the extremities. It results from vasoconstriction of the superficial thermoregulatory vessels as an exaggerated response to cold temperatures and/or to stress. It can occur primarily, without an associated autoimmune disease, or can relate to underlying rheumatic diseases such as scleroderma or mixed connective tissue disease.
CITATION STYLE
Sherber, N. S., & Wigley, F. M. (2014). Skin manifestations of raynaud’s phenomenon. In Skin Manifestations in Rheumatic Disease (pp. 185–190). Springer New York. https://doi.org/10.1007/978-1-4614-7849-2_23
Mendeley helps you to discover research relevant for your work.