Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis

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Abstract

Introduction The relevance of allergic rhinitis is unquestionable. This condition affectseople's quality of life and its incidence has increased over the last years. Objective Thus, this study aims to analyze the effectiveness of subcutaneous injectable immunotherapy in cases of nasal itching, sneeze, rhinorrhea and nasal congestion in allergic rhinitisatients. Methods In theresent study, the same researcher analyzed the records of 281atients. Furthermore, the researchers identified allergens throughuncture cutaneous tests using standardized extracts containing acari, fungi,et hair, flowerollen, and feathers. Then, theatients underwent treatment with subcutaneous specific immunotherapy, using four vaccine vials for desensitization, associated with environmental hygiene. The authors analyzed conditions of nasal itching, sneeze, rhinorrhea, and nasal congestion throughout the treatment, and assigned them with a score ranging from zero (0), meaning absence of these symptoms to three (3), for severe cases. The symptoms were statistically compared in the beginning, during, and after treatment. Results In this study, authors analyzed the cases distribution according to age and the evolution of symptomatology according to the scores, comparing allhases of treatment. The average score for the entireopulation studied was 2.08 before treatment and 0.44 at the end. These results represent an overall improvement of ∼79% in symptomatology of allergic rhinitis in the studiedopulation. Conclusion The subcutaneous immunotherapy as treatment of allergic rhinitis led to a reduction in all symptoms studied, improving the quality of life ofatients,roving itself as an important therapeutic tool for theseathological conditions.

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Lourenço, E. A., Caldeira, E. J., Carvalho, C. A. F., Cunha, M. R., Carvalho, M. V. H., & Passos, S. D. (2014, December 10). Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis. International Archives of Otorhinolaryngology. Georg Thieme Verlag. https://doi.org/10.1055/s-0035-1564437

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