Assessment of different laboratory tests for the diagnosis of novel coronavirus infections

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Abstract

Rapid diagnosis of coronavirus disease 2019 (COVID-19)-infected patients is urgent in making decisions on public health measures. There are different types of diagnostic tests, such as quantitative PCR assay, antibody, and antigen-based and CRISPR-based tests, which detect genetic materials, viral proteins, or human antibodies in clinical samples. However, the proper test should be highly sensitive, quick, and affordable to address this life-threatening situation. This review article highlights the advantages and disadvantages of each test and compares its different features, such as sensitivity, specificity, and limit of detection to reach a reliable conclusion. Moreover, the FDA- authorized kits and studies' approaches toward these have been compared to provide a better perspective to the researchers.

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Ghojoghi, R., Zamani, B., & Behbahani, A. B. (2022). Assessment of different laboratory tests for the diagnosis of novel coronavirus infections. Reviews and Research in Medical Microbiology, 33(3), 148–159. https://doi.org/10.1097/MRM.0000000000000285

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