Bovine viral diarrhea virus can cause acute disease in livestock, leading to economic losses. We show that Prostaglandin A1 inhibits bovine viral diarrhea virus replication in Madin-Darby bovine kidney cells (94% inhibition using 5 μg/mL). Light and electron microscopy of infected cells shows that Prostaglandin A1 also prevents virus-induced vacuolization, but at higher concentrations (10 μg/mL).
CITATION STYLE
Caldas, L. A., Freitas, T. R. P., Azevedo, R. C., & de Souza, W. (2018). Prostaglandin A1 inhibits the replication of bovine viral diarrhea virus. Brazilian Journal of Microbiology, 49(4), 785–789. https://doi.org/10.1016/j.bjm.2017.12.010
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