Stroke prevention with oral anticoagulants in patients with atrial fibrillation predisposes for bleeding. As a result, in select patient groups anticoagulation is withheld because of a perceived unfavorable risk-benefit ratio. Reasons for withholding anticoagulation can vary greatly between clinicians, often leading to discussion in daily clinical practice on the best approach. To guide clinical decision-making, we have reviewed available evidence on the most frequently reported reasons for withholding anticoagulation: previous bleeding, frailty and age, and an overall high bleeding risk.
CITATION STYLE
Seelig, J., Pisters, R., Hemels, M. E., Huisman, M. V., Cate, H. T., & Alings, M. (2019). When to withhold oral anticoagulation in atrial fibrillation - an overview of frequent clinical discussion topics. Vascular Health and Risk Management. Dove Medical Press Ltd. https://doi.org/10.2147/VHRM.S187656
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