Neovascularization in Models of Branch Retinal Vein Occlusion

Abstract

Branch retinal vein occlusion can be achieved in several species using laser photocoagulation with or without photodynamic agents. The neovascular response shows high variability within and between species. However, animal models of ischemia-associated intraocular neovascularization from branch retinal vein occlusion have been employed with success to demonstrate therapeutic effects of pharmaceutical agents and to study mechanisms of angiogenesis.