Overview of quantitative LC-MS techniques for proteomics and activitomics.

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Abstract

LC-MS is a useful technique for protein and peptide quantification. In addition, as a powerful tool for systems biology research, LC-MS can also be used to quantify post-translational modifications and metabolites that reflect biochemical pathway activity. This review discusses the different analytical techniques that use LC-MS for the quantification of proteins, their modifications and activities in a multiplex manner.

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Timms, J. F., & Cutillas, P. R. (2010). Overview of quantitative LC-MS techniques for proteomics and activitomics. Methods in Molecular Biology (Clifton, N.J.). https://doi.org/10.1007/978-1-60761-780-8_2

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